HRID734814

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID787

Hydroxylamine

H3NO

结构：CC1CCN(CCOc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2C=O)CC1

HCID86601135

未命名化合物

PRODUCTS

生成物

结构：CC1CCN(CCOc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2C=NO)CC1

HCID72984184

未命名化合物

PROCEDURE

实验过程

The product was obtained analogously to Example 14.1d starting from 5-[5-(4-chlorophenyl)pyridin-2-ylethynyl]-2-[2-(4-methylpiperidin-1-yl)ethoxy]benzaldehyde (Example 14.1c) and hydroxylamine. Yield: 40 mg (46% of theoretical); C28H28ClN3O2 (M=473.994); calc.: molpeak (M+H)+: 474/476 (Cl); found: molpeak (M+H)+: 474/476 (Cl); HPLC-MS: 5.68 minutes (method A).

WORKUP

后处理

customThe product was obtained analogously to Example 14.1d
custom5.68 minutes (method A)