BROMINE CHLORIDE (BrCl) → HCID 69057764, compound

HRID 734816Notes

Reaction equation

HRID 734816 reaction equation
Br[C:2]1[C:7]([Br:8])=[CH:6][C:5]([C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][CH:10]=2)=[CH:4][N:3]=1.[CH3:16][Si:17]([C:20]#[CH:21])([CH3:19])[CH3:18].BrCl>>[Br:8][C:7]1[C:2]([C:21]#[C:20][Si:17]([CH3:19])([CH3:18])[CH3:16])=[N:3][CH:4]=[C:5]([C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][CH:10]=2)[CH:6]=1

Participants

4

Reactant 3

HCID 61697BROMINE CHLORIDE (BrCl)2×HCID 66111TrimethylsilylacetyleneHCID 860770432,3-Dibromo-5-(4-chlorophenyl)pyridine

Product 1

HCID 69057764HCID 69057764, compound

Procedure

The product was prepared analogously to Example 7.1b starting from 2,3-dibromo-5-(4-chlorophenyl)pyridine and trimethylsilylacetylene. Yield: 1.00 g (95% of theoretical); C16H15BrClNSi (M=364.739); calc.: molpeak (M+H)+: 364/366/368 (BrCl); found: molpeak (M+H)+: 364/366/368 (BrCl).

Workup

  1. customThe product was prepared analogously to Example 7.1b

Sources & evidence

ORD record
ord-31e834c6425343c8a95011f90d5c9aac
Source dataset
uspto-grants-2009_09
Patent number
US07592358B2

Reaction notes

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