Tridecanoic acid → Ethyl{benzyl[4-(tridecanoylamino)benzyl]amino}(oxo)acetate

HRID 735825Notes

Reaction equation

HRID 735825 reaction equation
[CH2:1]([O:3][C:4](=[O:23])[C:5]([N:7]([CH2:15][C:16]1[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=1)[CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:6])[CH3:2].[C:24](O)(=[O:37])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36]>>[CH2:1]([O:3][C:4](=[O:23])[C:5]([N:7]([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:15][C:16]1[CH:21]=[CH:20][C:19]([NH:22][C:24](=[O:37])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])=[CH:18][CH:17]=1)=[O:6])[CH3:2]

Participants

3

Reactant 2

HCID 12530Tridecanoic acidHCID 67187687Ethyl[(4-aminobenzyl)(benzyl)amino](oxo)acetate

Product 1

HCID 67188066Ethyl{benzyl[4-(tridecanoylamino)benzyl]amino}(oxo)acetateYield 39%

Procedure

The same procedure as employed in the preparation of Example 5, step d using ethyl[(4-aminobenzyl)(benzyl)amino](oxo)acetate and tridecanoic acid gave the title compound as a colorless oil (39%). M−(ESI): 507.2. HPLC (Condition A), Rt: 7 min (HPLC purity-91.3%).

Workup

  1. customThe same procedure as employed in the preparation of Example 5, step d

Sources & evidence

ORD record
ord-deeadb137ac349a3977693e2dd5608ca
Source dataset
uspto-grants-2009_09
Patent number
US07592477B2

Reaction notes

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