HRID736715

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID787

Hydroxylamine

H3NO

结构：Cc1cc(COc2ccc(S(=O)(=O)N[C@@H]3CCCC[C@H]3C(=O)O)cc2)c2ccccc2n1

HCID68819595

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(COc2ccc(S(=O)(=O)N[C@@H]3CCCC[C@H]3C(=O)NO)cc2)c2ccccc2n1

HCID86607868

未命名化合物

收率 16%

PROCEDURE

实验过程

According to the procedure of Example 10, Step 2, the reaction of 186.8 mg (0.4 mmol) of trans-2-[({4-[(2-methylquinolin-4-yl)methoxy]phenyl}sulfonyl)amino]cyclohexanecarboxylic acid with hydroxylamine provided 31.8 mg of trans-N-hydroxy-2-[({4-[(2-methylquinolin-4-yl)methoxy]phenyl}sulfonyl)amino]cyclohexanecarboxamide in 16% yield. MS: 470.1 (M+H)+