2,2'-Bipyridine → 1,3,5-Trifluorobenzene

HRID 736958Notes

Reaction equation

HRID 736958 reaction equation
Cl[C:2]1[C:7]([F:8])=[C:6](Cl)[C:5]([F:10])=[C:4](Cl)[C:3]=1[F:12].C1C=CN=C(C2C=CC=CN=2)C=1>[Zn].Cl[Ni]Cl>[F:8][C:7]1[CH:2]=[C:3]([F:12])[CH:4]=[C:5]([F:10])[CH:6]=1

Participants

5

Reactant 2

HCID 14742,2'-BipyridineHCID 675731,3,5-Trichloro-2,4,6-trifluorobenzene

Product 1

HCID 97451,3,5-Trifluorobenzene

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 24385Nickel DichlorideCatalyst

Procedure

In Russ. J. of Org. Chem., vol. 36, 1, pp. 132-33 (2000) describes the dehalogenation of 1,3,5-trichlorotrifluorobenzene by means of zinc in the presence of NiCl2 and bipyridine to give 1,3,5-trifluorobenzene.

Sources & evidence

ORD record
ord-b80bfc5beb70417dbc87902599aa7ed0
Source dataset
uspto-grants-2009_09
Patent number
US07595426B2

Reaction notes

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