反应详情

To a suspension of the product of step 2 (59 g, 183 mmol) in a mixture of CH2Cl2 (300 mL), MeOH (1 L), t-BuOH (350 mL) was added a suspension of oxone (248 g, 403 mmol) in 700 mL of H2O. The mixture was stirred for 1 h. Saturated NaHCO3 was added slowly until all solid dissolved. The resulting mixture was extracted with Et2O. The ether extracts were dried (Na2SO4) and concentrated to give 39.3 g of the title compound.

1. additionwas added
2. dissolutiondissolved
3. extractionThe resulting mixture was extracted with Et2O
4. dry with materialThe ether extracts were dried (Na2SO4)
5. concentrationconcentrated