4-Bromobenzaldehyde → (1,1'-Biphenyl)-4-carboxaldehyde

HRID 742077Notes

Reaction equation

C([C:3]1[C:4]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[C:5]2[C:10](=[CH:11][CH:12]=1)OC(C1C=CC=CC=1)=C(O)C2=O)=C.BrC1C=CC([CH:32]=[O:33])=CC=1>>[C:21]1([C:4]2[CH:3]=[CH:12][CH:11]=[CH:10][CH:5]=2)[CH:22]=[CH:23][C:24]([CH:32]=[O:33])=[CH:25][CH:26]=1

Participants

Reactant 2

HCID 707414-Bromobenzaldehyde

HCID 19427220HCID 19427220, compound

Product 1

HCID 76689(1,1'-Biphenyl)-4-carboxaldehyde

Procedure

Alternatively, a vinyl phenyl hydroxyflavone may be prepared by synthesizing 4-styrene trimethyltin and combining it with 4-bromobenzaldehyde to produce 4'-vinyl, 4-biphenyl aldehyde. This intermediate compound is then reacted with 2-hydroxyacetophenone to produce the vinyl phenyl hydroxyflavone. This reaction scheme proceeds as follows: ##STR14##

Sources & evidence

ORD record: ord-4e94cd988df94006b2c4c4b8676c3497
Source dataset: uspto-grants-1996_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05552551

Reaction notes

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