Hydrochloric Acid → 2-(2-{2-[2-(3-Methoxyphenyl)ethyl]phenoxy}-ethyl]-1-methylpyrrolidine hydrochloride

HRID 743247Notes

Reaction equation

HRID 743247 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][CH2:10][C:11]2[CH:25]=[CH:24][CH:23]=[CH:22][C:12]=2[O:13][CH2:14][CH2:15][CH:16]2[CH2:20][CH2:19][CH2:18][N:17]2[CH3:21])[CH:6]=[CH:7][CH:8]=1.[ClH:26]>>[ClH:26].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][CH2:10][C:11]2[CH:25]=[CH:24][CH:23]=[CH:22][C:12]=2[O:13][CH2:14][CH2:15][CH:16]2[CH2:20][CH2:19][CH2:18][N:17]2[CH3:21])[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 158968632-(2-{2-[2-(3-Methoxyphenyl)ethyl]phenoxy}ethyl)-1-methylpyrrolidine

Product 1

HCID 194238542-(2-{2-[2-(3-Methoxyphenyl)ethyl]phenoxy}-ethyl]-1-methylpyrrolidine hydrochlorideYield 36%

Procedure

Following a procedure similar to that described in Example 35(a), 5.70 g of 2-(2-{2-[2-(3-methoxyphenyl)ethyl]phenoxy}ethyl)-1-methylpyrrolidine [prepared as described in step (a) above] were converted to the hydrochloride, to give 4.89 g (yield 36%) of the title compound as colorless crystals.

Sources & evidence

ORD record
ord-0da05a922f3d43e0866a0f01a6299495
Source dataset
uspto-grants-1996_09
Patent number
US05556864

Reaction notes

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