反应详情

0.85 mL (15 mmol) acetaldehyde were added dropwise to 2.0 g (15 mmol) indolin-2-one and 0.20 mL piperidine in 20 mL methanol. The reaction mixture was refluxed for 3 h and then evaporated down. The residue was triturated in diisopropylether and suction filtered.

1. temperatureThe reaction mixture was refluxed for 3 h
2. customevaporated down
3. customThe residue was triturated in diisopropylether
4. filtrationsuction filtered