反应详情

Combine 15.0 g (0.086 mole) of 2-(4-chlorophenyl)ethyl chloride and 20.98 g (0.08 mole) of triphenylphosphine. Heat the mixture under a nitrogen atmosphere at 110°-120° C. for 3.5 days. Follow the progress of the reaction by thin layer chromatography on silica gel (hexanes). At the completion of the reaction triturate the resulting solid with 250 ml of anhydrous ether to afford the title compound.

1. temperatureHeat the mixture under a nitrogen atmosphere at 110°-120° C. for 3.5 days
2. customthe progress of the reaction by thin layer chromatography on silica gel (hexanes)
3. customAt the completion of the reaction triturate the resulting solid with 250 ml of anhydrous ether