Triphenylphosphine → HCID 23313744, compound

HRID 745536Notes

Reaction equation

HRID 745536 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9]Cl)=[CH:4][CH:3]=1.[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[Cl-:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][P+:17]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 11776TriphenylphosphineHCID 37903592-(4-Chlorophenyl)ethyl chloride

Product 1

HCID 23313744HCID 23313744, compound

Procedure

Combine 15.0 g (0.086 mole) of 2-(4-chlorophenyl)ethyl chloride and 20.98 g (0.08 mole) of triphenylphosphine. Heat the mixture under a nitrogen atmosphere at 110°-120° C. for 3.5 days. Follow the progress of the reaction by thin layer chromatography on silica gel (hexanes). At the completion of the reaction triturate the resulting solid with 250 ml of anhydrous ether to afford the title compound.

Workup

  1. temperatureHeat the mixture under a nitrogen atmosphere at 110°-120° C. for 3.5 days
  2. customthe progress of the reaction by thin layer chromatography on silica gel (hexanes)
  3. customAt the completion of the reaction triturate the resulting solid with 250 ml of anhydrous ether

Sources & evidence

ORD record
ord-0612775a3e4a4e2580ce088047f721a5
Source dataset
uspto-grants-1986_07
Patent number
US04599344

Reaction notes

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