反应详情

In a hydrogen atmosphere 0.50 g (3.5 mmol) 4-methyl-isoquinoline, 50 mg platinum dioxide in 50 mL methanol and 3.5 mL 1M aqueous hydrochloric acid solution were hydrogenated at RT and 3 bar for 4 h. After removal of the catalyst by suction filtering the reaction mixture was evaporated down. A mixture of educt and product was obtained, which was reacted further without any further purification.

1. customwere hydrogenated at RT
2. customAfter removal of the catalyst by suction
3. filtrationfiltering the reaction mixture
4. customwas evaporated down
5. additionA mixture of educt
6. customproduct was obtained
7. customwhich was reacted further without any further purification