反应详情

Under an argon atmosphere 16 mL (0.10 mmol) triethylsilane were slowly added dropwise to 2.3 g (9.3 mmol) methyl (4-nitro-1H-indol-3-yl)-oxo-acetate in 18 mL trifluoroacetic acid while cooling with ice. Then the mixture was stirred for a further 3 h at RT and evaporated down. The residue was dried and then triturated with diisopropylether, suction filtered and dried in the air.

1. temperaturewhile cooling with ice
2. customevaporated down
3. customThe residue was dried
4. customtriturated with diisopropylether, suction
5. filtrationfiltered
6. customdried in the air