Ethyl Acetate → HCID 70454371, compound

HRID 746122Notes

Reaction equation

HRID 746122 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([CH3:20])([CH:17]=[CH:18][CH3:19])[CH2:11][N:12]1[CH2:16][CH2:15][CH2:14][CH2:13]1.[CH2:21]([Br:25])[CH:22]=[CH:23][CH3:24].C(OCC)(=[O:28])C>>[Br-:25].[C:21]([N+:12]1([CH2:11][C:10]([CH3:20])([CH:17]=[CH:18][CH3:19])[CH2:9][C:3]2[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=2[Cl:1])[CH2:16][CH2:15][CH2:14][CH2:13]1)(=[O:28])/[CH:22]=[CH:23]/[CH3:24]

Participants

4

Reactant 3

HCID 8857Ethyl AcetateHCID 1224142-Butene, 1-bromo-HCID 54512673HCID 54512673, compound

Product 1

HCID 70454371HCID 70454371, compound

Procedure

A solution of 31.2 g of N-[3-(2,4-dichlorophenyl)-2-methyl-2-prop-1-en-1-yl-propyl]-pyrrolidine and 27 g of crotyl bromide in 250 ml of ethyl acetate is refluxed for 5 hours. The mixture is then stirred for 15 hours at room temperature and the crystalline product which is obtained is filtered off, washed with ether and dried in vacuo. 15 g of the desired product is obtained; m.p.: 128° C.

Workup

  1. customthe crystalline product which is obtained
  2. filtrationis filtered off
  3. washwashed with ether
  4. customdried in vacuo

Sources & evidence

ORD record
ord-42c6a34ad2ad4b83911c941b8c62b180
Source dataset
uspto-grants-1986_07
Patent number
US04602930

Reaction notes

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