反应详情

A mixture of 6-chloro-7-methyl-chroman-4-one (20 g, 101.71 mmol), NBS (19.9 g, 111.88 mmol), and AIBN (4.17 g, 25.43 mmol) in anhydrous CCl4 (300 mL) was heated at reflux in 24 h. The mixture was cooled, filtered the solid. The filtrate was concentrated and used in the next step without purification.

1. temperaturewas heated
2. temperatureat reflux in 24 h
3. temperatureThe mixture was cooled
4. filtrationfiltered the solid
5. concentrationThe filtrate was concentrated
6. customused in the next step without purification