反应详情

A mixture of 4-trifluoromethylthiosalicylic acid (2.5 g, 11 mmol), 2-cyanopyridine (1.2 g, 11 mmol) and pyridine (10 ml) was refluxed for 10 hrs. After cooling, the precipitated crystals were collected by filtration and recrystallized from tetrahydrofuran-hexane to give the titled compound (1.9 g, 54%).

1. temperaturewas refluxed for 10 hrs
2. temperatureAfter cooling
3. filtrationthe precipitated crystals were collected by filtration
4. customrecrystallized from tetrahydrofuran-hexane