Diisopropyl Ether → HCID 22939382, compound

HRID 748364Notes

Reaction equation

HRID 748364 reaction equation
[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[S:5][C:4]([C:12]2[N:17]=[C:16]([S:18]([CH2:20][C:21]([O:23]C(C)(C)C)=[O:22])=[O:19])[CH:15]=[CH:14][CH:13]=2)=[N:3]1.C(OC(C)C)(C)C>FC(F)(F)C(O)=O>[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[S:5][C:4]([C:12]2[N:17]=[C:16]([S:18]([CH2:20][C:21]([OH:23])=[O:22])=[O:19])[CH:15]=[CH:14][CH:13]=2)=[N:3]1

Participants

4

Reactant 2

HCID 7914Diisopropyl EtherHCID 59750212HCID 59750212, compound

Product 1

HCID 22939382HCID 22939382, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

tert-Butyl [[6-(4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]sulfinyl]acetate (0.12 g, 0.30 mmol) was dissolved in trifluoroacetic acid (5 ml), and the mixture was stirred for 0.5 hr. Diisopropyl ether was added to the mixture. The obtained crystals were recrystallized from ethanol to give the titled compound (0.081 g, 79%) as pale yellow crystals.

Workup

  1. customThe obtained crystals were recrystallized from ethanol

Sources & evidence

ORD record
ord-7252aab5492141de9d47af08c2ba9327
Source dataset
uspto-grants-2008_07
Patent number
US07399759B2

Reaction notes

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