Diisopropyl Ether → HCID 22939501, compound

HRID 748365Notes

Reaction equation

HRID 748365 reaction equation
[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[S:5][C:4]([C:12]2[N:17]=[C:16]([S:18]([CH2:21][C:22]([O:24]C(C)(C)C)=[O:23])(=[O:20])=[O:19])[CH:15]=[CH:14][CH:13]=2)=[N:3]1.C(OC(C)C)(C)C>FC(F)(F)C(O)=O>[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[S:5][C:4]([C:12]2[N:17]=[C:16]([S:18]([CH2:21][C:22]([OH:24])=[O:23])(=[O:20])=[O:19])[CH:15]=[CH:14][CH:13]=2)=[N:3]1

Participants

4

Reactant 2

HCID 7914Diisopropyl EtherHCID 59750238HCID 59750238, compound

Product 1

HCID 22939501HCID 22939501, compoundYield 55.2%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

tert-Butyl {[6-(4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]sulfonyl}acetate (0.10 g, 0.24 mmol) was dissolved in trifluoroacetic acid (5 ml), and the mixture was stirred f or 0.5 hr. Diisopropyl ether was added to the mixture. The obtained precipitates were recrystallized from ethanol to give the titled compound (0.048 g, 55%) as pale yellow crystals.

Workup

  1. customThe obtained precipitates
  2. customwere recrystallized from ethanol

Sources & evidence

ORD record
ord-05180f35a9014f1e9bd492497eaf8851
Source dataset
uspto-grants-2008_07
Patent number
US07399759B2

Reaction notes

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