m-Chloroperbenzoic acid → HCID 86596470, compound

HRID 748444Notes

Reaction equation

HRID 748444 reaction equation
[CH2:1]([N:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=2)[C:4]1=[O:14])[CH3:2].ClC1C=CC=C(C(OO)=[O:23])C=1>C(OCC)(=O)C>[CH2:1]([N+:3]1([O-:23])[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=2)[C:4]1=[O:14])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 22939319HCID 22939319, compound

Product 1

HCID 86596470HCID 86596470, compoundYield 74.3%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

1-Ethyl-3-(4-pyridyl)-2-imidazolidinone (0.71 g, 3.7 mmol) and 3-chloroperbenzoic acid (77%, 1.67 g, 7.4 mmol) were dissolved in ethyl acetate (20 ml), and the mixture was stirred at room temperature for 40 hrs. The solvent was evaporated, and the residue was subjected to a silica gel column chromatography. The fractions eluted with methanol-ethyl acetate (2:3, v/v) were collected and concentrated to give the titled compound (0.57 g, 73%) as white crystals.

Workup

  1. customThe solvent was evaporated
  2. washThe fractions eluted with methanol-ethyl acetate (2:3
  3. customv/v) were collected
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-33b96b75b83e43aba1a91c8bb792ed95
Source dataset
uspto-grants-2008_07
Patent number
US07399759B2

Reaction notes

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