HRID74951

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

HCID81531

Diisopropylethylamine

C8H19N

HCID7128323

(1S,2S)-2-Aminocyclohexanecarboxylic Acid

C7H13NO2

结构：Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(Cl)cnc32)cc1

HCID57597747

5-Chloro-1-(4-methylbenzene-1-sulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

C20H22BClN2O4S

结构：Cc1ccc(S(=O)(=O)n2cc(-c3ncc(F)c(S(C)=O)n3)c3cc(Cl)cnc32)cc1

HCID67285321

未命名化合物

PRODUCTS

生成物

结构：OC1CCCCC1(O)Nc1nc(-c2c[nH]c3ncc(Cl)cc23)ncc1F

HCID86762729

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

溶剂HCID8028

Tetrahydrofuran

C4H8O

溶剂HCID22177404

未命名化合物

PROCEDURE

实验过程

(1S,2S)-2-aminocyclohexanecarboxylic acid, iPr2NEt, Na2CO3, THF—CH3CN (3:1), 135° C. microwave; (b) 1N LiOH, THF, microwave, 120° C.; (c) 4NHCl-dioxane, EtOH, 70° C.