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HRID749548

反应详情

EQUATION

反应方程式

HRID 749548 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CC(C)c1ccc(CBr)cc1
HCID47719

p-Cymene, bromo-

C10H13Br

结构：N#CC(C#N)CCC(F)(F)F
HCID22185761

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)c1ccc(CC(C#N)(C#N)CCC(F)(F)F)cc1
HCID22235051

未命名化合物

收率 85%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Using 0.21 g of 4-isopropylbenzyl bromide, 3 ml of N,N-dimethylformamide, 0.05 g of sodium hydride (60% in oil), and 0.17 g of (3,3,3-trifluoropropyl)malononitrile, and according to the process described in the Production Example 26, there was obtained 0.24 g of 2-(4-isopropylbenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (35)).