Beta-Nitrostyrene → HCID 59752542, compound

HRID 749705Notes

Reaction equation

HRID 749705 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]1)=O)(C)(C)C.[CH3:15][O:16][C:17]1[CH:24]=[CH:23][C:20]([CH2:21][NH2:22])=[CH:19][CH:18]=1.[N+]([CH:28]=[CH:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)([O-])=O>CCO>[CH3:15][O:16][C:17]1[CH:24]=[CH:23][C:20]([CH2:21][N:22]2[C:11]3[CH2:10][CH2:9][NH:8][CH2:13][C:12]=3[C:29]([C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)=[CH:28]2)=[CH:19][CH:18]=1

Participants

5

Reactant 3

HCID 7626Beta-NitrostyreneHCID 754524-MethoxybenzylamineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 59752542HCID 59752542, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound (0.19 g) was prepared from 1.51 g of 4-oxo-piperidine-1-carboxylic acid tert-butyl ester, 1.0 mL of 4-methoxybenzylamine, and 1.13 g of (2-nitro-vinyl)-benzene, using EtOH as the solvent and omitting SiO2. MS (ESI): exact mass calculated for C21H22N2O, 318.17; found, m/z 319.2 [M+H]+.

Sources & evidence

ORD record
ord-87ef6537d63c4eae8d2e09dfc3d60cd0
Source dataset
uspto-grants-2008_07
Patent number
US07402680B2

Reaction notes

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