HRID750200

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7738

(4-Methoxyphenyl)methanol

C8H10O2

HCID69155739

未命名化合物

PRODUCTS

产物

HCID69157233

未命名化合物

PROCEDURE

实验过程

The present compound was synthesized by a method similar to that in Example 200 and using 2-[(benzyloxycarbonyl)(methyl)amino]-6-chloro-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid (200 mg) and 4-methoxybenzyl alcohol. A colorless powder (110 mg). HPLC analysis (Agilent 1100 system): purity 96% (retention time: 4.30 min). MS (ESI+): 583 (M+H), 585.

WORKUP

后处理

customThe present compound was synthesized by a method similar to that in Example 200

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-fb8124114b03433ebe5983089b05bae5
来源数据集: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07402595B2
来源说明: uspto-grants-2008_07

反应SMILES

[CH2:1]([O:8][C:9]([N:11]([CH3:33])[N:12]1[C:21]([C:22]([OH:24])=[O:23])=[C:20]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19]2[C:14](=[CH:15][CH:16]=[C:17]([Cl:31])[CH:18]=2)[C:13]1=[O:32])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:34][O:35][C:36]1[CH:43]=[CH:42][C:39]([CH2:40]O)=[CH:38][CH:37]=1>>[CH3:34][O:35][C:36]1[CH:43]=[CH:42][C:39]([CH2:40][O:23][C:22]([C:21]2[N:12]([N:11]([C:9]([O:8][CH2:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)=[O:10])[CH3:33])[C:13](=[O:32])[C:14]3[C:19]([C:20]=2[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[CH:18][C:17]([Cl:31])=[CH:16][CH:15]=3)=[O:24])=[CH:38][CH:37]=1