反应详情

9.00 g (29.69 mmol) N-[2-(4-iodo-phenyl)-1-methyl-ethyl]-acetamide (I52.1) are added to 150 mL HCl (4N) and the reaction mixture is stirred at reflux over night. Then the mixture is diluted with soda lye and extracted with EtOAc. The organic layer is dried with Na2SO4 and the solvent is removed in vacuo.

1. temperatureat reflux over night
2. additionThen the mixture is diluted with soda lye
3. extractionextracted with EtOAc
4. dry with materialThe organic layer is dried with Na2SO4
5. customthe solvent is removed in vacuo