反应详情

30.0 g (0.20 mol) of 2,4-dichloropyrimidine, 30.9 g (0.20 mol) of ethyl N-methylglycinate and 61.0 g (0.60 mol) of triethylamine in 200 ml of dioxane are stirred at 50° C. for 10 min. The mixture is filtered off with suction and the mother liquor is concentrated to half the original volume. A solid crystallizes out, which is filtered off with suction. The mother liquor is concentrated, the residue is stirred with petroleum ether and the product is filtered off.

1. filtrationThe mixture is filtered off with suction
2. concentrationthe mother liquor is concentrated to half the original volume
3. customA solid crystallizes out, which
4. filtrationis filtered off with suction
5. concentrationThe mother liquor is concentrated
6. filtrationthe product is filtered off