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HRID78417

反应详情

EQUATION

反应方程式

HRID 78417 的结构方程式

REACTANTS

反应物

4
结构：On1nnc2ccccc21
HCID75771

1-Hydroxybenzotriazole

C6H5N3O

结构：CC1(C)C(C(=O)O)C1(C)C
HCID152115

2,2,3,3-Tetramethylcyclopropanecarboxylic acid

C8H14O2

结构：CCN=C=NCCCN(C)C.Cl
HCID2723939

1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride

C8H18ClN3

结构：Cc1nc(N)sc1N1CCOCC1
HCID86618905

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(NC(=O)C2C(C)(C)C2(C)C)sc1N1CCOCC1
HCID86618904

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCN(CC)CC
溶剂HCID8471

Triethylamine

C6H15N

PROCEDURE

实验过程

A mixture of 4-methyl-5-morpholin-4-yl-thiazol-2-ylamine (prepared using the method described in Christopher et al., Bioorganic and Medicinal Chemistry Letters 2004, 14(22), 5521-5525), N-(3-dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride, 1-hydroxybenzotriazole, triethylamine, and 2,2,3,3-tetramethylcyclopropanecarboxylic acid were processed using the method described in Example 58 to afford the title compound. MS (ESI) m/z 324 (M+H)+.

WORKUP

后处理

  1. customprepared