Dimethylformamide → 3-(4-Fluoro-benzenesulfonyl)-1-trityloxy-azepan-2-one

HRID 798928Notes

Reaction equation

HRID 798928 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]([C:7]([CH2:8][S:9](=[O:10])(=[O:11])[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1)=[O:19])[O:20][C:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[C:40](=[O:41])([O-:42])[O-:43].[CH3:51][CH2:52][O:53][C:54]([CH3:55])=[O:56].[Cs+:44].[Cs+:45].[O:46]=[CH:47][N:48]([CH3:49])[CH3:50]>>[CH2:2]1[CH2:3][CH2:4][CH2:5][N:6]([O:20][C:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[C:7](=[O:19])[CH:8]1[S:9](=[O:10])(=[O:11])[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 86619941N-(4-Bromo-butyl)-2-(4-fluoro-benzenesulfonyl)-N-trityloxy-acetamide

Product 1

HCID 685136933-(4-Fluoro-benzenesulfonyl)-1-trityloxy-azepan-2-one

Sources & evidence

ORD record
ord-5ae93d3c3a824e9d86ac9cbc3a905363
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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