Potassium Cation → 3-Cyclobutyl-7-[(5-nitro-2-thienyl)oxy]-2,3,4,5-tetrahydro-1H-3-benzazepine

HRID 799288Notes

Reaction equation

HRID 799288 reaction equation
[Br:1][c:2]1[s:3][c:4]([N+:7](=[O:8])[O-:9])[cH:5][cH:6]1.[C:26](=[O:27])([O-:28])[O-:29].[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[CH:10]1([N:14]2[CH2:15][CH2:16][c:17]3[c:18]([cH:21][c:22]([OH:25])[cH:23][cH:24]3)[CH2:19][CH2:20]2)[CH2:11][CH2:12][CH2:13]1.[K+:30].[K+:31]>>[c:2]1([O:25][c:22]2[cH:21][c:18]3[c:17]([cH:24][cH:23]2)[CH2:16][CH2:15][N:14]([CH:10]2[CH2:11][CH2:12][CH2:13]2)[CH2:20][CH2:19]3)[s:3][c:4]([N+:7](=[O:8])[O-:9])[cH:5][cH:6]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 832222-Bromo-5-nitrothiopheneHCID 100820813-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OL

Product 1

HCID 103828953-Cyclobutyl-7-[(5-nitro-2-thienyl)oxy]-2,3,4,5-tetrahydro-1H-3-benzazepine

Sources & evidence

ORD record
ord-eda108fba135407a81af286204d2a7b2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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