Tetrahydrofuran → 1-Acetyl-4-phenyl-6-(4-n-propylbenzoyl)amino-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline

HRID 799466Notes

Reaction equation

HRID 799466 reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[C:5]([CH3:22])([CH3:23])[CH2:6][C:7]([CH3:15])([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:8]2[cH:9][c:10]([NH2:14])[cH:11][cH:12][c:13]21.[CH2:24]([CH2:25][CH3:26])[c:27]1[cH:28][cH:29][c:30]([C:31](=[O:32])[Cl:33])[cH:34][cH:35]1.[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1>>[C:1]([CH3:2])(=[O:3])[N:4]1[C:5]([CH3:22])([CH3:23])[CH2:6][C:7]([CH3:15])([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:8]2[cH:9][c:10]([NH:14][C:31]([c:30]3[cH:29][cH:28][c:27]([CH2:24][CH2:25][CH3:26])[cH:35][cH:34]3)=[O:32])[cH:11][cH:12][c:13]21

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 1042934-Propylbenzoyl chlorideHCID 28370841-(6-amino-2,2,4-trimethyl-4-phenyl-3,4-dihydroquinolin-1(2H)-yl)ethanone

Product 1

HCID 113968851-Acetyl-4-phenyl-6-(4-n-propylbenzoyl)amino-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline

Sources & evidence

ORD record
ord-8d0fd37808154d41904c397d28df89c6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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