Dichloromethane → (S)-4-Isobutyl-5,5-diphenyloxazolidin-2-one

HRID 799699Notes

Reaction equation

HRID 799699 reaction equation
[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[Cl:1][C:2](=[O:3])[O:4][C:5]([Cl:6])([Cl:7])[Cl:8].[Cl:36][CH2:37][Cl:38].[NH2:9][CH:10]([C:11]([OH:12])([c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)[c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[CH2:25][CH:26]([CH3:27])[CH3:28]>>[C:2]1(=[O:3])[NH:9][CH:10]([CH2:25][CH:26]([CH3:27])[CH3:28])[C:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[O:12]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 10426DiphosgeneHCID 33723782-Amino-4-methyl-1,1-diphenylpentan-1-ol

Product 1

HCID 4588682(S)-4-Isobutyl-5,5-diphenyloxazolidin-2-one

Sources & evidence

ORD record
ord-8de2c7bb90a147158d32ba4547e85c58
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…