Ammonium → tert-Butyl 4-(4-amino-2-cyanophenyl)piperazine-1-carboxylate

HRID 799977Notes

Reaction equation

HRID 799977 reaction equation
[CH3:29][CH2:30][OH:31].[Cl-:1].[Fe:28].[N+:4]([O-:5])(=[O:6])[c:7]1[cH:8][cH:9][c:10]([N:15]2[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]2)[c:11]([C:12]#[N:13])[cH:14]1.[NH4+:2].[OH2:3]>>[NH2:4][c:7]1[cH:8][cH:9][c:10]([N:15]2[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]2)[c:11]([C:12]#[N:13])[cH:14]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312ChlorideHCID 702EthanolHCID 962WaterHCID 23925IronHCID 22227995tert-Butyl 4-(2-cyano-4-nitrophenyl)piperazine-1-carboxylate

Product 1

HCID 22227872tert-Butyl 4-(4-amino-2-cyanophenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-8f86fa69f5514600a9e909bae5ef5936
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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