Hydrochloric Acid → 3-(2,3-dihydro-1H-indol-5-yl)-1-ethyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one

HRID 800056Notes

Reaction equation

[CH2:1]([CH3:2])[n:3]1[c:4](=[O:28])[n:5](-[c:12]2[cH:13][c:14]3[c:18]([cH:19][cH:20]2)[N:17]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:16][CH2:15]3)[c:6]2[n:7][cH:8][cH:9][cH:10][c:11]12.[CH3:30][CH2:31][O:32][C:33]([CH3:34])=[O:35].[ClH:29]>>[CH2:1]([CH3:2])[n:3]1[c:4](=[O:28])[n:5](-[c:12]2[cH:13][c:14]3[c:18]([cH:19][cH:20]2)[NH:17][CH2:16][CH2:15]3)[c:6]2[n:7][cH:8][cH:9][cH:10][c:11]12

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 8857Ethyl Acetate

HCID 58577726tert-butyl 5-(1-ethyl-2-oxo-1,2-dihydro-3H-imidazo[4,5-b]pyridin-3-yl)-2,3-dihydro-1H-indole-1-carboxylate

Product 1

HCID 585772823-(2,3-dihydro-1H-indol-5-yl)-1-ethyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one

Sources & evidence

ORD record: ord-05754f29644a4d3c961714bc57722de6
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…