Hydrochloric Acid → 5-amino-1,5-dimethyl-7,8-dihydro-6H-quinolin-2-one

HRID 800122Notes

Reaction equation

HRID 800122 reaction equation
[CH3:17][I:18].[CH3:29][N:30]([CH3:31])[CH:32]=[O:33].[ClH:3].[H-:1].[NH2:4][C:5]1([CH3:16])[c:6]2[cH:7][cH:8][c:9](=[O:15])[nH:10][c:11]2[CH2:12][CH2:13][CH2:14]1.[Na+:28].[Na+:2].[OH-:27].[OH:19][C:20]([CH:21]=[CH:22][C:23](=[O:24])[OH:25])=[O:26]>>[NH2:4][C:5]1([CH3:16])[c:6]2[cH:7][cH:8][c:9](=[O:15])[n:10]([CH3:20])[c:11]2[CH2:12][CH2:13][CH2:14]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 7232-Butenedioic acidHCID 923Sodium ion2×HCID 961HydroxideHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 166653HydrideHCID 9989805HCID 9989805, compound

Product 1

HCID 103977135-amino-1,5-dimethyl-7,8-dihydro-6H-quinolin-2-one

Sources & evidence

ORD record
ord-416745e12bfe40c7974c2bc3c6b65e98
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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