Tetrahydrofuran → 4-Chloro-N-[2-(3-methoxyphenyl)ethyl]aniline

HRID 800388Notes

Reaction equation

HRID 800388 reaction equation
[Al+3:21].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([CH2:10][c:11]2[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][cH:16]2)=[O:19])[cH:6][cH:7]1.[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][CH2:9][CH2:10][c:11]2[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][cH:16]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 2666228HCID 2666228, compound

Product 1

HCID 133619124-Chloro-N-[2-(3-methoxyphenyl)ethyl]aniline

Sources & evidence

ORD record
ord-8ee62651bc97409aada2bd211907ef84
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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