Acetic Acid → (3-Bromo-6-ethoxy-pyrazolo[5,1-b][1,3]thiazol-7-yl)-carbamic acid tert-butyl ester
Reaction equation
[Br:25][C:26]([F:27])([F:28])[C:29]([F:30])([F:31])[Br:32].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([O:16][CH2:17][CH3:18])[n:10][n:11]2[c:12]1[s:13][cH:14][cH:15]2)=[O:19].[CH2:20]([Li:21])[CH2:22][CH2:23][CH3:24].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:35][C:36](=[O:37])[OH:38].[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44].[Cl-:33].[NH4+:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([O:16][CH2:17][CH3:18])[n:10][n:11]2[c:12]1[s:13][cH:14][c:15]2[Br:25])=[O:19]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-e6bfc823a14a45968186d9f7aa6a1e61
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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