Dimethylformamide → 6-Bromo-3-methanesulfonyl-2-methyl-4-morpholin-4-yl-quinoline

HRID 800884Notes

Reaction equation

HRID 800884 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([Cl:17])[c:6]([S:13](=[O:14])(=[O:15])[CH3:16])[c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1.[CH2:18]1[CH2:19][O:20][CH2:21][CH2:22][NH:23]1.[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([N:23]3[CH2:18][CH2:19][O:20][CH2:21][CH2:22]3)[c:6]([S:13](=[O:14])(=[O:15])[CH3:16])[c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8083MorpholineHCID 81531DiisopropylethylamineHCID 120016236-Bromo-4-chloro-3-methanesulfonyl-2-methyl-quinoline

Product 1

HCID 120018106-Bromo-3-methanesulfonyl-2-methyl-4-morpholin-4-yl-quinoline

Sources & evidence

ORD record
ord-11ac565a6c2643c6b2487c61a9160797
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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