Tetrahydrofuran → tert-butyl N-(2-methyl-3-oxopropyl)carbamate

HRID 801201Notes

Reaction equation

HRID 801201 reaction equation
[Al+3:2].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:7][O:8][N:9]([C:10]([CH:11]([CH2:12][NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH3:21])=[O:22])[CH3:23].[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[CH:10]([CH:11]([CH2:12][NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH3:21])=[O:22]

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 86607767Tert-butyl {3-[methoxy(methyl)amino]-2-methyl-3-oxopropyl}carbamate

Product 1

HCID 19791000tert-butyl N-(2-methyl-3-oxopropyl)carbamate

Sources & evidence

ORD record
ord-d6e6ce21e51f47a98c79b62241af0f90
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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