Potassium Cation → N-isopropyl-2-(4-(2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)piperidin-1-yl)acetamide

HRID 801230Notes

Reaction equation

HRID 801230 reaction equation
[C:36](=[O:37])([O-:38])[O-:39].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH:42]([CH3:43])([CH3:44])[NH:45][C:46]([CH2:47][Cl:48])=[O:49].[CH:8]([CH3:9])([CH3:10])[n:11]1[n:12][cH:13][n:14][c:15]1-[c:16]1[cH:17][n:18]2[c:24]([n:25]1)-[c:23]1[c:22]([cH:29][c:28]([CH:30]3[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]3)[cH:27][cH:26]1)[O:21][CH2:20][CH2:19]2.[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[K+:40].[K+:41]>>[CH:8]([CH3:9])([CH3:10])[n:11]1[n:12][cH:13][n:14][c:15]1-[c:16]1[cH:17][n:18]2[c:24]([n:25]1)-[c:23]1[c:22]([cH:29][c:28]([CH:30]3[CH2:31][CH2:32][N:33]([CH2:47][C:46]([NH:45][CH:42]([CH3:43])[CH3:44])=[O:49])[CH2:34][CH2:35]3)[cH:27][cH:26]1)[O:21][CH2:20][CH2:19]2

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6422Trifluoroacetic acidHCID 8028TetrahydrofuranHCID 19660Carbonate IonHCID 761712-chloro-N-(1-methylethyl)acetamideHCID 582045509-Piperidin-4-yl-2-(2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine

Product 1

HCID 71014678N-isopropyl-2-(4-(2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)piperidin-1-yl)acetamide

Sources & evidence

ORD record
ord-cf068890672549c5a4e7134642166464
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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