Hydrochloric Acid → 5-(1,1-Dimethylethyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-1-phenyl-1H-pyrazolo[3,4-b]pyridine

HRID 801331Notes

Reaction equation

HRID 801331 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:1][C:2]([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]2[c:8]([nH:9][c:10]1=[O:11])[n:12](-[c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[n:13][cH:14]2.[CH3:36][N:37]([CH3:38])[CH:39]=[O:40].[Cl:28][CH2:29][c:30]1[n:31]([CH3:35])[n:32][cH:33][n:34]1.[ClH:27].[Cs+:25].[Cs+:26]>>[CH3:1][C:2]([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]2[c:8]([n:9][c:10]1[O:11][CH2:29][c:30]1[n:31]([CH3:35])[n:32][cH:33][n:34]1)[n:12](-[c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[n:13][cH:14]2

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 104192195-(Chloromethyl)-1-methyl-1H-1,2,4-triazoleHCID 1358542811,7-Dihydro-5-(1,1-dimethylethyl)-1-phenylpyrazolo[3,4-b]pyridin-6-one

Product 1

HCID 99251755-(1,1-Dimethylethyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-1-phenyl-1H-pyrazolo[3,4-b]pyridine

Sources & evidence

ORD record
ord-8450b3f2c253411b864a1072a06bfbf4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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