Tetrahydrofuran → 3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

HRID 801770Notes

Reaction equation

HRID 801770 reaction equation
[CH2:56]1[O:57][CH2:58][CH2:59][CH2:60]1.[Cl:30][c:31]1[c:32]([CH:39]([CH3:40])[OH:41])[c:33]([Cl:38])[cH:34][cH:35][c:36]1[F:37].[N:42]([C:43]([O:44][CH:45]([CH3:46])[CH3:47])=[O:48])=[N:49][C:50]([O:51][CH:52]([CH3:53])[CH3:54])=[O:55].[OH:1][c:2]1[c:3]([N+:8](=[O:9])[O-:10])[n:4][cH:5][cH:6][cH:7]1.[c:11]1([P:12]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:25][cH:26][cH:27][cH:28][cH:29]1>>[O:1]([c:2]1[c:3]([N+:8](=[O:9])[O-:10])[n:4][cH:5][cH:6][cH:7]1)[CH:39]([c:32]1[c:31]([Cl:30])[c:36]([F:37])[cH:35][cH:34][c:33]1[Cl:38])[CH3:40]

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 270573-Hydroxy-2-nitropyridineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 167700681-(2,6-Dichloro-3-fluorophenyl)ethan-1-ol

Product 1

HCID 469422963-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine

Sources & evidence

ORD record
ord-2965f6a0bbe24f749d04a8ade869d510
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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