Tetrahydrofuran → 4-[(2-Butyl-benzofuran-3-yl)-hydroxy-methyl]-phenol

HRID 802127Notes

Reaction equation

HRID 802127 reaction equation
[Al+3:24].[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[o:6][c:7]2[c:8]([c:9]1[C:10]([c:11]1[cH:12][cH:13][c:14]([OH:17])[cH:15][cH:16]1)=[O:18])[cH:19][cH:20][cH:21][cH:22]2.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[H-:23].[H-:26].[H-:27].[H-:28].[Li+:25]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[o:6][c:7]2[c:8]([c:9]1[CH:10]([c:11]1[cH:12][cH:13][c:14]([OH:17])[cH:15][cH:16]1)[OH:18])[cH:19][cH:20][cH:21][cH:22]2

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 96670(2-Butylbenzofuran-3-yl) (4-hydroxyphenyl) ketoneHCID 104727Aluminum CationHCID 166653Hydride4×

Product 1

HCID 234456214-[(2-Butyl-benzofuran-3-yl)-hydroxy-methyl]-phenol

Sources & evidence

ORD record
ord-e5f6cd57d5c64bf49566af213977c21e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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