Dimethylformamide → tert-Butyl 3-formyl-5-phenylpyridin-2-ylcarbamate

HRID 802384Notes

Reaction equation

HRID 802384 reaction equation
[CH2:29]([Li:30])[CH2:31][CH2:32][CH3:33].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:21][N:22]([CH3:23])[CH2:24][CH2:25][N:26]([CH3:27])[CH3:28].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38].[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[n:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][c:9]([CH:35]=[O:34])[c:10]([NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[n:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 8037N,N,N',N'-TetramethylethylenediamineHCID 58671538tert-Butyl 5-phenylpyridin-2-ylcarbamateHCID 178418339Butyllithium

Product 1

HCID 58671547tert-Butyl 3-formyl-5-phenylpyridin-2-ylcarbamate

Sources & evidence

ORD record
ord-3ab7def7a94b427c958d088fa3956775
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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