Dichloromethane → tert-butyl (NE)-N-[[(8-bromo-4,5-dihydrothieno[3,2-d][1]benzoxepine-2-carbonyl)amino]-methylsulfanylmethylidene]carbamate

HRID 802697Notes

Reaction equation

HRID 802697 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:18]1)[O:7][CH2:8][CH2:9][c:10]1[c:11]-2[s:12][c:13]([C:15](=[O:16])[OH:17])[cH:14]1.[C:30](=[O:31])([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[NH:37][C:38]([S:39][CH3:40])=[NH:41].[CH3:19][CH2:20][N:21]=[C:22]=[N:23][CH2:24][CH2:25][CH2:26][N:27]([CH3:28])[CH3:29].[CH3:45][N:46]([c:47]1[cH:48][cH:49][n:50][cH:51][cH:52]1)[CH3:53].[Cl:42][CH2:43][Cl:44]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:18]1)[O:7][CH2:8][CH2:9][c:10]1[c:11]-2[s:12][c:13]([C:15](=[O:17])[N:41]=[C:38]([NH:37][C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[S:39][CH3:40])[cH:14]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 579001638-Bromo-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxylic acidHCID 137319820tert-butyl N-[(methylsulfanyl)methanimidoyl]carbamate

Product 1

HCID 178503937tert-butyl (NE)-N-[[(8-bromo-4,5-dihydrothieno[3,2-d][1]benzoxepine-2-carbonyl)amino]-methylsulfanylmethylidene]carbamate

Sources & evidence

ORD record
ord-32a630f845eb4ff681a0395557ee9704
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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