Dimethylformamide → 3-Tert-butyldimethylsilyloxy-2,5-difluorobenzaldehyde

HRID 802762Notes

Reaction equation

HRID 802762 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[O:8][c:9]1[c:10]([F:16])[cH:11][cH:12][c:13]([F:15])[cH:14]1.[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH:17]([Li:18])([CH2:19][CH3:20])[CH3:21].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[O:8][c:9]1[c:10]([F:16])[c:11]([CH:23]=[O:22])[cH:12][c:13]([F:15])[cH:14]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 11230299tert-Butyl(2,5-difluorophenoxy)dimethylsilaneHCID 178418400CID 53628100

Product 1

HCID 113463223-Tert-butyldimethylsilyloxy-2,5-difluorobenzaldehyde

Sources & evidence

ORD record
ord-7af1399766124b06ba9267b755939d41
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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