Methanethiol → 2-Amino-4-chloro-5-(2,4-dichlorophenyl)-6-methylthio pyrimidine

HRID 802892Notes

Reaction equation

HRID 802892 reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:19][SH:20].[CH3:21][O:22][CH2:23][CH2:24][O:25][CH2:26][CH2:27][N:28]([CH2:29][CH2:30][O:31][CH2:32][CH2:33][O:34][CH3:35])[CH2:36][CH2:37][O:38][CH2:39][CH2:40][O:41][CH3:42].[Cu:43].[NH2:1][c:2]1[n:3][c:4]([Cl:17])[c:5](-[c:9]2[c:10]([Cl:16])[cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[c:6]([Cl:8])[n:7]1.[Na:18]>>[NH2:1][c:2]1[n:3][c:4]([S:20][CH3:19])[c:5](-[c:9]2[c:10]([Cl:16])[cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[c:6]([Cl:8])[n:7]1

Participants

7

Reactant 6

HCID 878MethanethiolHCID 8028TetrahydrofuranHCID 23978CopperHCID 112414Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]-HCID 5360545SodiumHCID 197050544,6-Dichloro-5-(2,4-dichlorophenyl)pyrimidin-2-amine

Product 1

HCID 197050792-Amino-4-chloro-5-(2,4-dichlorophenyl)-6-methylthio pyrimidine

Sources & evidence

ORD record
ord-4ae040f10c3e496394da1bbfc366e6f3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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