Potassium Cation → 3-(1-(4-(2-methoxyethoxy)-2,3-difluorophenyl)-1H-tetrazol-5-yl)-5-bromopyridin-2-amine

HRID 803416Notes

Reaction equation

HRID 803416 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH3:29][O:30][CH2:31][CH2:32][Br:33].[CH3:37][CH2:38][O:39][C:40]([CH3:41])=[O:42].[I-:35].[K+:27].[K+:28].[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:22])[cH:6][c:7]1-[c:8]1[n:9][n:10][n:11][n:12]1-[c:13]1[c:14]([F:21])[c:15]([F:20])[c:16]([OH:19])[cH:17][cH:18]1.[Na+:34].[OH2:36]>>[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:22])[cH:6][c:7]1-[c:8]1[n:9][n:10][n:11][n:12]1-[c:13]1[c:14]([F:21])[c:15]([F:20])[c:16]([O:19][CH2:32][CH2:31][O:30][CH3:29])[cH:17][cH:18]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 923Sodium ionHCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 30165Iodide IonHCID 809722-Bromoethyl methyl etherHCID 582937904-(5-(2-amino-5-bromopyridin-3-yl)-1H-tetrazol-1-yl)-2,3-difluorophenol

Product 1

HCID 582938153-(1-(4-(2-methoxyethoxy)-2,3-difluorophenyl)-1H-tetrazol-5-yl)-5-bromopyridin-2-amine

Sources & evidence

ORD record
ord-f9e3a22bab654aee8e9834bc8b08ffde
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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