HRID803531

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID13387

N-Methyl-2-pyrrolidone

C5H9NO

HCID16099239

未命名化合物

HCID24938057

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cccc2c1cnn2-c1ccccc1)C(F)(F)F

HCID57615944

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d372312cc976498cb8b07734ac136566
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:38][N:39]1[CH2:40][CH2:41][CH2:42][C:43]1=[O:44].[ClH:21].[F:1][c:2]1[cH:3][cH:4][c:5]([O:19][CH3:20])[c:6]([C:8]([CH2:9][C:10]2([C:13]([F:14])([F:15])[F:16])[O:11][CH2:12]2)([CH3:17])[CH3:18])[cH:7]1.[c:22]1(-[n:28]2[n:29][cH:30][c:31]3[c:32]([NH2:37])[cH:33][cH:34][cH:35][c:36]23)[cH:23][cH:24][cH:25][cH:26][cH:27]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:19][CH3:20])[c:6]([C:8]([CH2:9][C:10]([OH:11])([CH2:12][NH:37][c:32]2[c:31]3[cH:30][n:29][n:28](-[c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[c:36]3[cH:35][cH:34][cH:33]2)[C:13]([F:14])([F:15])[F:16])([CH3:17])[CH3:18])[cH:7]1