Hydrochloric Acid → 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42

HRID 803924Notes

Reaction equation

HRID 803924 reaction equation
[CH3:33][OH:34].[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([S:17]([CH3:18])(=[O:19])=[O:20])[n:15][cH:16]3)[n:21]([CH3:24])[c:22]2=[O:23])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[ClH:32].[NH2:25][c:26]1[cH:27][cH:28][n:29][cH:30][cH:31]1>>[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH:25][c:26]4[cH:27][cH:28][n:29][cH:30][cH:31]4)[n:15][cH:16]3)[n:21]([CH3:24])[c:22]2=[O:23])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 17274-AminopyridineHCID 105961576-(2,6-Dichlorophenyl)-8-methyl-2-methylsulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one

Product 1

HCID 53278892-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42

Sources & evidence

ORD record
ord-60d89833474f4237a59fbde111a7b278
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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