Potassium Cation → 2-(4-(4-Diphenylmethyl-piperazin-1-yl)-3-hydroxy-butyl]isoindolin-1,3-dione

HRID 804584Notes

Reaction equation

HRID 804584 reaction equation
[C:36](=[O:37])([O-:38])[O-:39].[CH:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[N:30]1[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]1.[K+:40].[K+:41].[O:1]1[CH:2]([CH2:3][CH2:4][N:5]2[C:6](=[O:15])[c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]3[C:13]2=[O:14])[CH2:16]1.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46]>>[OH:1][CH:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:15])[c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]2[C:13]1=[O:14])[CH2:16][N:33]1[CH2:32][CH2:31][N:30]([CH:17]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:35][CH2:34]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 70048BenzhydrylpiperazineHCID 3394332-[2-(oxiran-2-yl)ethyl]-2,3-dihydro-1H-isoindole-1,3-dione

Product 1

HCID 223976852-(4-(4-Diphenylmethyl-piperazin-1-yl)-3-hydroxy-butyl]isoindolin-1,3-dione

Sources & evidence

ORD record
ord-cabaddd1e40b4669aee96cbbf7a5654e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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