Bromide ion → 1,3-Difluoro-5-[3-hydroxy-3-(thiazol-2-yl)propen-3-yl]benzene
Reaction equation
[Br-:16].[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[CH:17](=[CH2:18])[Mg+:19].[ClH:20].[F:1][c:2]1[cH:3][c:4]([C:9](=[O:10])[c:11]2[s:12][cH:13][cH:14][n:15]2)[cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[cH:3][c:4]([C:9]([OH:10])([c:11]2[s:12][cH:13][cH:14][n:15]2)[CH:17]=[CH2:18])[cH:5][c:6]([F:8])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-17d9cc1112eb4c908d1e52f1a30b2946
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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