4-Aminophenol → 4-(4-Aminophenoxy)-N-methylpicolinamide

HRID 804960Notes

Reaction equation

HRID 804960 reaction equation
[CH3:9][C:10]([CH3:11])([O-:12])[CH3:13].[Cl:15][c:16]1[cH:17][c:18]([C:22](=[O:23])[NH:24][CH3:25])[n:19][cH:20][cH:21]1.[K+:14].[K+:26].[K+:27].[NH2:1][c:2]1[cH:3][cH:4][c:5]([OH:6])[cH:7][cH:8]1.[O-:28][C:29]([O-:30])=[O:31].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:16]2[cH:17][c:18]([C:22](=[O:23])[NH:24][CH3:25])[n:19][cH:20][cH:21]2)[cH:7][cH:8]1

Participants

7

Reactant 6

HCID 4034-AminophenolHCID 813Potassium Cation3×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 14768144-Chloro-N-methylpicolinamideHCID 45749132-Methylpropan-2-olate

Product 1

HCID 166551294-(4-Aminophenoxy)-N-methylpicolinamide

Sources & evidence

ORD record
ord-40c16fb9124e48b39c392ae6d3971969
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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